Pioneering the treatment
of joint infection.

About ForCast

At ForCast, we are focused on the development of effective treatments for periprosthetic joint infection (PJI) via targeted drug delivery to improve patient outcomes following joint replacement.

ForCast Orthopedics was founded by an experienced life sciences entrepreneur and leading orthopedic surgeon.

Our proprietary platform automates a treatment method that has been demonstrated in clinical research to achieve superior patient outcomes compared with the standard of care for periprosthetic joint infections (PJI).

We believe our approach to localized treatment of PJI will become the new gold standard, replacing the inadequate standard of care, which currently suffers from low success rates, high cost and high patient morbidity including limb loss.

Our Mission

Our mission is to modernize the standard of care for periprosthetic joint infections and improve the quality of life for the growing population of joint replacement patients.

ForCast Leadership Team

Scientific Advisors

Richard Berger, MD

Advisor, SAB

Carl Deirmengian, MD

Advisor, SAB

Angela Hewlett MD, MS

Advisor, SAB

Alex McLaren, MD

Advisor, SAB

Leo Whiteside, MD

Advisor, SAB

Recognitions & Awards

Anterior Hip Foundation Competition Win

ForCast Orthopedics today announced that it won the Shark Tank competition at the Anterior Hip Foundation (AHF) meeting held in Nashville on June 6, 2025.
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Orphan Drug Designation
from FDA

ForCast Orthopedics was granted Orphan Drug Designation by the US Food and Drug Administration (FDA) for ForCast’s lead program, FC001, for the treatment of periprosthetic joint infection (PJI).
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QIDP Designation
from FDA

ForCast Orthopedics was granted Qualified Infectious Disease Product (QIDP) Designation by the US Food and Drug Administration (FDA) for ForCast’s lead program, FC001, for the treatment of periprosthetic joint infection (PJI).
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NSF SBIR
Award

ForCast Orthopedics has received Phase I, Phase II and Phase IIB grants from the National Science Foundation to advance the development of its novel treatment approach through proof-of-concept efficacy models.

Colorado OEDIT
Grant

ForCast Orthopedics received a Colorado Advanced Industry Award from the Office of Economic Development & International Trade to further develop its proprietary drug delivery system in orthopedics.

News & Press Releases

Denver, CO – August 5, 2025 – ForCast Orthopedics today announced the initial closing of a Series A equity financing round to support the development of its novel therapies for periprosthetic joint infection (PJI). The financing was led by OrthoInnovations, LLC, and its Managing Partner, Charles A. DeCook, MD, a renowned serial entrepreneur and leading orthopedic surgeon.
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Denver, CO – June 17, 2025 – ForCast Orthopedics today announced that it won the Shark Tank competition at the Anterior Hip Foundation (AHF) meeting held in Nashville on June 6, 2025. Among seven companies pitching to a panel of five experts, ForCast was recognized for its groundbreaking approach to the treatment of periprosthetic joint infection (PJI).
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Denver, CO – May 1, 2025 – ForCast Orthopedics today announced the closing of a $10M Series A equity financing round to support the development of its novel therapies for periprosthetic joint infection (PJI). The financing was led by OrthoInnovations LLC, and its Managing Partner, Charles A. DeCook, MD, a renowned serial entrepreneur and leading orthopedic surgeon.
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Denver, CO – June 27, 2023 – ForCast Orthopedics today announced that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation for ForCast’s lead program, FC001, for the treatment of periprosthetic joint infection (PJI).
Read More

Denver, CO – February 28, 2023 – ForCast Orthopedics today announced that the US Food and Drug Administration (FDA) has granted Qualified Infectious Disease Product (QIDP) Designation for ForCast’s lead program, FC001, for the treatment of periprosthetic joint infection (PJI).
Read More

Contact

To learn more about ForCast: info@forcastortho.com